Associate Professor of Epidemiology and Biostatistics

Department of Epidemiology and Biostatistics

* scheng@hust.edu.cn

Academic Areas

Cancer Genomics, Precision Health

Research Interests

Study the molecular pathogenesis of complex diseases, such as cancer, through integration of multi-omics data.

Personalized risk prediction and targeted therapeutic design based on analysis of genetics data

Courses Taught

Biostatistics

Awards and Honors

2013           Basic Science EDGE Award, University of Michigan, USA

2012-2013  Barbour Scholarship, University of Michigan, USA

Education

2009-2014        Ph.D., University of Michigan, Ann Arbor, MI, USA

2005-2009        B.S., National University of Singapore, Singapore

Professional/working Experience

2018-present  Associate Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

2015-2018       Research Fellow, Duke-NUS Medical School, Singapore

Past and ongoing projects, funding, programs

2019-2021  Lung adenocarcinoma-associated alternative splicing regulatory network based on RNA-seq analysis, HUST, PI

Select Publications

Journal Article

1.    Thekkeparambil Chandrabose S, Sriram S, Subramanian S, Cheng S, Ong WK, Rozen S, Kasim NHA, Sugii S (2018). Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming. Stem Cell Research & Therapy 9(1):68

2.       Cheng S and Brooks CL III (2015). Protein-protein interfaces in viral capsids are structurally unique. Journal of Molecular Biology 427: 3613-24.

3.       Cheng S, Zhang Y and Brooks CL III (2015). PCalign: a method to quantify physico-chemical similarity of protein-protein interfaces. BMC Bioinformatics 16: 33.

4.       Cheng S and Brooks CL III (2013). Capsid proteins are segregated in structural fold space. PLoS Computational Biology 9: e1002905.

5.       Strunk BS, Loucks CR, Su M, Vashisth H, Cheng S, Schilling J, Brooks CL III, Karbstein K, Skiniotis G (2011). Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates. Science 333(6048):1449-53.