Professor of Epidemiology and Biostatistics
Associate Dean
Department of Epidemiology and Biostatistics
* miaoxp@mail.hust.edu.cn
Academic Areas
Molecular epidemiology / Genetic epidemiology
Research Interests
Epidemiological and biochemical approaches to investigate the associations between genetic variants and susceptibility to common cancers, with an emphasis in characterization of biological functions as the underlying molecular mechanisms.
Epidemiological studies to investigate gene-environment, gene-gene interactions and phenotype-genotype correlation in the risk of digestive cancers.
Selected Professional Affiliations
Academic Editor, Cancer Medicine
Member of Editorial Board, Chinese Diseases Prevention Journal (Zhonghua Yufang Yixue Zazhi)
Member, Chinese Preventive Medicine Association
Member, Chinese Anti-Cancer Association
Member, Genetics Society of China
Reviewer for peer-reviewed journals, including Nat Genet, Gastroenterology, Epidemiologic Reviews, Cancer Res, Hum Mol Genet, Hum Mutat, Hum Genet, Carcinogenesis,Cancer, Int J Cancer, Lung Cancer, Cancer Epidemiol, et al.C
Courses Taught
Epidemiology
Awards and Honors
2008 the 2nd Prize of National Science and Technology Progress Award
2006 the 2nd Prize of Natuonal Natural Science Award
2005 the 1st Prize of Beijing Natural Science Award
2005 the 2nd Prize of Natural Science Award from Ministry of Health P.R.China
Education
2000-2005 Ph.D., Peking Union Medical College (PUMC), Beijing, China
1995-2000 B.S., Zhejiang University, Zhejiang, China
Professional/working Experience
2009-present Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2005-2006 Postdoctoral Fellow, University of Hong Kong, Hong Kong
2005-2009 Assistant Professor, University of Hong Kong, Hong Kong
Past and ongoing projects, funding, programs
2011-2013 Genetic variants in spindle-assembly checkpoint complex and susceptibility to colorectal cancer, NSFC, PI
2012-2015 Genetic and funcational annotation of polymorphisms in TGF-β pathway and their assocaitons with colorectal cancer, NSFC, PI
2013-2015 Epidemiology, National Natural Science Foundation of China for excellent young scientist, PI
2017-2020 Genetic variants in lncRNA:miRNA binding regions and risk of pancreatic cancer. NSFC, PI
Select Publications
Books, Patents
1. 2017 Miao Xiaoping, Cancer, in Epidemiology. Edited by Zhan Siyan et al.
2. 2017 Miao Xiaoping, Epidemiological progress of malignant tumors, in Progress in Epidemiology. Edited by Ye Dongqing et al.
3. 2014 Miao Xiaoping, Pancreatic cancer, in Cancer Molecular Epidemiology. Edited by Shen Hongbing et al.
Journal Article
Full list can be found at http://www.researcherid.com/rid/C-4336-2011
Corresponding author
1. Tian J, Wang Z, Mei S, Yang N, Yang Y, Ke J, Zhu Y, Gong Y, Zou D, Peng X, Wang X, Wan H, Zhong R, Chang J, Gong J, Han L, Miao X. CancerSplicingQTL: a database for genome-wide identification of splicing QTLs in human cancer. Nucleic Acids Res. 2019;47(D1):D909-D916.
2. Yang Y, Peng X, Ying P, Tian J, Li J, Ke J, Zhu Y, Gong Y, Zou D, Yang N, Wang X, Mei S, Zhong R, Gong J, Chang J, Miao X. AWESOME: a database of SNPs that affect protein post-translational modification. Nucleic Acids Res. 2019;47(D1):D874-D880.
3. Gong J, Wan H, Mei S, Ruan H, Zhang Z, Liu C, Guo AY, Diao L, Miao X, Han L. Pancan-meQTL: a database to systematically evaluate the effects of genetic variants on methylation in human cancer. Nucleic Acids Res. 2019;47(D1):D1066-D1072
4. Chang J, Zhong R, Tian J, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Zhu Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Wu T, Wu C*, Miao X*, Lin D. Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma. Nat Genet. 2018; 50(3):338-343.
5. Gong J, Tian J, Lou J, Wang X, Ke J, Li J, Yang Y, Gong Y, Zhu Y, Zou D, Peng X, Yang N, Mei S, Zhong R, Chang J, Miao X*. A polymorphic MYC response element in KBTBD11 influences colorectal cancer risk, especially in interaction with an MYC-regulated SNP rs6983267. Ann Oncol. 2018;29(3):632-639
6. Gong J, Mei S, Liu C, Xiang Y, Ye Y, Zhang Z, Feng J, Liu R, Diao L, Guo AY, Miao X*, Han L*. PancanQTL: systematic identification of cis-eQTLs and trans-eQTLs in 33 cancer types. Nucleic Acids Res. 2018;46(D1):D971-D976.
7. Chang J, Tian J, Zhu Y, Zhong R, Zhai K, Li J, Ke J, Han Q, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Yang M, Wang L, Wu C*, Lin D*, Miao X*.Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations. Nat Commun. 2018;9(1):3688
8. Chang J, Tian J, Yang Y, Zhong R, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Gong Y, Zhu Y, Zou D, Peng X, Huang K, Miao X. A rare missense variant in TCF7L2 associates with colorectal cancer risk by interacting with a GWAS-identified regulatory variant in the MYC enhancer. Cancer Res. 2018;78(17):5164-5172.
9. Li J, Chang J, Tian J, Ke J, Zhu Y, Yang Y, Gong Y, Zou D, Peng X, Yang N, Mei S, Wang X, Cheng L, Hu W, Gong J, Zhong R, Miao X. A rare variant P507L in TPP1 interrupts TPP1-TIN2 interaction, influences telomere length, and confers colorectal cancer risk in Chinese population. Cancer Epidemiol Biomarkers Prev. 2018;27(9):1029-1035.
10. Zou D, Lou J, Ke J, Mei S, Li J, Gong Y, Yang Y, Zhu Y, Tian J, Chang J, Zhong R, Gong J*, Miao X*. Integrative expression quantitative trait locus-based analysis of colorectal cancer identified a functional polymorphism regulating SLC22A5 expression. Eur J Cancer. 2018;93:1-9.
