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Chaolong Wang

【Source: | Date:2019-06-04 】


Professor of Epidemiology and Biostatistics     undefined

Department of Epidemiology and Biostatistics

* chaolong@hust.edu.cn

Academic Areas

Statistical and Population GenomicsGenetic Epidemiology, Bioinformatics, Biostatistics

Research Interests

Statistical and computational methods for population-genetic data analysis

Application of integrative genomics approaches to understand the etiology of complex diseases

Development of risk prediction methods and disease prevention strategies based on multi-omics data

Population structure, admixture, and inference of human evolutionary histor

Courses Taught

Medical Statistics

Awards and Honors

2013     Charles J. Epstein Award semifinalist, American Society of Human Genetics

2012     Stellar Abstract Award in the 6th Annual PQG Conference, Harvard University

2011      International Student Research Fellowship, Howard Hughes Medical Institute

2011      Rackham Predoctoral Fellowship, University of Michigan

2011      DeLill Nasser Award, Genetics Society of America

2008    Program in Biomedical Sciences Fellowship, University of Michigan

Education

2004-2008      B.S. in Physics, Peking University, Beijing, China

2008-2011        M.A. in Statistics, University of Michigan, Ann Arbor, MI, USA

2008-2011        M.S. in Bioinformatics, University of Michigan, Ann Arbor, MI, USA

2008-2012       Ph.D. in Bioinformatics, University of Michigan, Ann Arbor, MI, USA

2012-2014        Research Fellow, Biostatistics, Harvard School of Public Health, Boston, MA, USA

Professional/working Experience

2018-Present   Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

2015-2018        Senior Research Scientist, Genome Institute of Singapore, Agency of Science Technology and Research (A*STAR), Singapore

2016-2018        Adjunct Assistant Professor, Duke-National University of Singapore Medical School, Singapore

Select Publications

Journal Article

(* Co-first author; # Corresponding author)

1.        J Dou*, B Sun*, X Sim, JD Hughes, DF Reilly, ES Tai, J Liu, C Wang#. Estimation of kinship coefficient in structured and admixed populations using sparse sequencing data. PLoS Genetics. 2017; 13: e1007021.

2.       D Taliun, S Chothani, S Schonherr, L Forer, M Boehnke, GR Abecasis, C Wang#. LASER server: ancestry tracing with genotypes or sequence reads. Bioinformatics. 2017; 33: 2056-2058.

3.       H Chen*, C Wang*, MP Conomos, AM Stilp, Z Li, T Sofer, AA Szpiro, W Chen, JM Brehm, JC Celedon, S Redline, GJ Papanicolaou, TA Thornton, CC Laurie, K Rice, X Lin. Control for population structure and relatedness for binary traits in genetic association studies via logistic mixed models. American Journal of Human Genetics. 2016; 98: 653-666.

4.       C Wang#, X Zhan, L Liang, GR Abecasis, X Lin. Improved ancestry estimation for both genotyping and sequencing data using projection Procrustes analysis and genotype imputation. American Journal of Human Genetics. 2015; 96: 926-937.

5.       C Wang#, X Zhan, J Bragg-Gresham, HM Kang, D Stambolian, E Chew, K Branham, J Heckenlively, The FUSION Study, RS Fulton, RK Wilson, ER Mardis, X Lin, A Swaroop, S Zollner, GR Abecasis#. Ancestry estimation and control of population stratification for sequence-based association studies. Nature Genetics. 2014; 46: 409-415.

6.       X Zhan*, DE Larson*, C Wang*, DC Koboldt, Y Sergeev, 52 other coauthors, ER Mardis, A Swaroop, GR Abecasis. Identification of a rare coding variant in Complement 3 associated with age-related macular degeneration. Nature Genetics. 2013; 45: 1375-1379

7.       C Wang#, KB Schroeder, NA Rosenberg. A maximum-likelihood method to correct for allelic dropout in microsatellite data with no replicate genotypes. Genetics. 2012; 192: 651-669.

8.      C Wang#, S Zollner, NA Rosenberg. A quantitative comparison of the similarity between genes and geography in worldwide human populations. PLoS Genetics. 2012; 8: e1002886

9.       C Wang, ZA Szpiech, J Degnan, M Jakobsson, TJ Pemberton, JA Hardy, AB Singleton, NA Rosenberg. Comparing spatial maps of human population-genetic variation using Procrustes analysis. Statistical Applications in Genetics and Molecular Biology. 2010; 9: Article 13