Professor of Epidemiology and Biostatistics
Department of Epidemiology and Biostatistics
* chaolong@hust.edu.cn
Academic Areas
Statistical and Population Genomics,Genetic Epidemiology, Bioinformatics, Biostatistics
Research Interests
Statistical and computational methods for population-genetic data analysis
Application of integrative genomics approaches to understand the etiology of complex diseases
Development of risk prediction methods and disease prevention strategies based on multi-omics data
Population structure, admixture, and inference of human evolutionary histor
Courses Taught
Medical Statistics
Awards and Honors
2013 Charles J. Epstein Award semifinalist, American Society of Human Genetics
2012 Stellar Abstract Award in the 6th Annual PQG Conference, Harvard University
2011 International Student Research Fellowship, Howard Hughes Medical Institute
2011 Rackham Predoctoral Fellowship, University of Michigan
2011 DeLill Nasser Award, Genetics Society of America
2008 Program in Biomedical Sciences Fellowship, University of Michigan
Education
2004-2008 B.S. in Physics, Peking University, Beijing, China
2008-2011 M.A. in Statistics, University of Michigan, Ann Arbor, MI, USA
2008-2011 M.S. in Bioinformatics, University of Michigan, Ann Arbor, MI, USA
2008-2012 Ph.D. in Bioinformatics, University of Michigan, Ann Arbor, MI, USA
2012-2014 Research Fellow, Biostatistics, Harvard School of Public Health, Boston, MA, USA
Professional/working Experience
2018-Present Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2015-2018 Senior Research Scientist, Genome Institute of Singapore, Agency of Science Technology and Research (A*STAR), Singapore
2016-2018 Adjunct Assistant Professor, Duke-National University of Singapore Medical School, Singapore
Select Publications
Journal Article
(* Co-first author; # Corresponding author)
1. J Dou*, B Sun*, X Sim, JD Hughes, DF Reilly, ES Tai, J Liu, C Wang#. Estimation of kinship coefficient in structured and admixed populations using sparse sequencing data. PLoS Genetics. 2017; 13: e1007021.
2. D Taliun, S Chothani, S Schonherr, L Forer, M Boehnke, GR Abecasis, C Wang#. LASER server: ancestry tracing with genotypes or sequence reads. Bioinformatics. 2017; 33: 2056-2058.
3. H Chen*, C Wang*, MP Conomos, AM Stilp, Z Li, T Sofer, AA Szpiro, W Chen, JM Brehm, JC Celedon, S Redline, GJ Papanicolaou, TA Thornton, CC Laurie, K Rice, X Lin. Control for population structure and relatedness for binary traits in genetic association studies via logistic mixed models. American Journal of Human Genetics. 2016; 98: 653-666.
4. C Wang#, X Zhan, L Liang, GR Abecasis, X Lin. Improved ancestry estimation for both genotyping and sequencing data using projection Procrustes analysis and genotype imputation. American Journal of Human Genetics. 2015; 96: 926-937.
5. C Wang#, X Zhan, J Bragg-Gresham, HM Kang, D Stambolian, E Chew, K Branham, J Heckenlively, The FUSION Study, RS Fulton, RK Wilson, ER Mardis, X Lin, A Swaroop, S Zollner, GR Abecasis#. Ancestry estimation and control of population stratification for sequence-based association studies. Nature Genetics. 2014; 46: 409-415.
6. X Zhan*, DE Larson*, C Wang*, DC Koboldt, Y Sergeev, 52 other coauthors, ER Mardis, A Swaroop, GR Abecasis. Identification of a rare coding variant in Complement 3 associated with age-related macular degeneration. Nature Genetics. 2013; 45: 1375-1379
7. C Wang#, KB Schroeder, NA Rosenberg. A maximum-likelihood method to correct for allelic dropout in microsatellite data with no replicate genotypes. Genetics. 2012; 192: 651-669.
8. C Wang#, S Zollner, NA Rosenberg. A quantitative comparison of the similarity between genes and geography in worldwide human populations. PLoS Genetics. 2012; 8: e1002886
9. C Wang, ZA Szpiech, J Degnan, M Jakobsson, TJ Pemberton, JA Hardy, AB Singleton, NA Rosenberg. Comparing spatial maps of human population-genetic variation using Procrustes analysis. Statistical Applications in Genetics and Molecular Biology. 2010; 9: Article 13