Professor of Environmental Medicine

Department of Environmental Medicine

* xtshenlab@hust.edu.cn

Academic Areas

Molecular imprinting, Small molecules recognition;

Research Interests

Polymer monolithic columns for nano scale peptide separation;

Nanoparticles stabilized emulsion polymerization for small molecules recognition.

MIPs towards protein or cells.

Controlled release of drugs based on hybrid colloidosomes.

Molecular imprinted inorganic crystals.

Mechanism study in molecular imprinting.

Education

2007.1-2010.3         Ph.D. College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology

2004.6-2006.12      M.S., College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology.

1998.9-2002.6         B.S. Department of Chemistry, Huazhong University of Science and Technology.

Professional/working Experience

2015.2-Present        Professor , School of Public Health, Tongji MedicalCollege, Huazhong University of Science and Technology.

2014.9-2015.2          Guest researcher in department of biomedical science in Mamlo University in Sweden.

2013.2-2014.6          Researcher in G&T Septech AS (University of Oslo) in Norway.

2010.3-2013.1          Postdoctoral researcher in pure and applied biochemistry department of Chemical Center of Lund University in Sweden

Past and ongoing projects, funding, programs

Catalytic degradation of typocal antibiotics using molecularly imprinted MOFs . The National Natural Science Foundation of China Project (PI: 2017/01-2020/12)

The next generation of bacterial imprinteing based on bacterial chemotaxis. National Natural Science Foundation of China project (PI: 2019/01-2022/12)

Application of aggregation induced luminescence based on molecular recognition in detection of metabolic markers in diabetes mellitus. Central University Basic Research Fund (PI: 2016/04-2018/12).

Study on the oxidation of cyclic growth hormone inhibitor cyclic peptides by multiplex nano-mimetic enzyme catalysis system. Central University Basic Research Fund (PI: 2015/05-2016/12).

Study on extraction of peptides from plasma by molecular imprinting and electromembrane extraction. Hubei Youth Technology Morning Light Project, (PI: 2015-2016)

Select Publications

Books

1.        Shen, X.; Huang, C.; Ye, L., Generation of Janus Molecularly Imprinted Polymer Particles. In Synthetic Antibodies. 2017, 353-362 (Humana Press)

2.       Shen, X., Molecularly Imprinted Catalysts, Molecularly Imprinted Photocatalysts. 2016,.211-228 (Elsevier)

Patents

1.        Shen X, Chen Z, Liu X, A synthetic method for photoreduction of hexavalent chromium ion-imprinted polymer materialsan. No. 201710534799.6

2.       Zhu L, Shen X, Tang H, A synthetic method for artificial antibody-based composite photocatalyst. No: 200610019453.4

3.       Zhu L, Luo W, Shen X, Tang H, A synthetic method for molecularly imprinted adsorbent on SiO2 particle surface. No: 200810046661.2

Journal Article

*Corresponding author

1.         Lin, B.; Wan, L.; Sun, X.; Huang, C.; Pedersen-Bjergaard, S.; Shen, X., Electromembrane extraction of high level substances: A novel approach for selective recovery of templates in molecular imprinting. J. Membrane Sci., 2018, 568, 30-39

2.        Wan, L.; Chen, Z.; Huang, C.*; Shen, X.* Core-shell molecularly imprinted particles; TrAC, Trends Anal. Chem., 2017, 95, 110-121

3.        Sun X.; Li J.; Jin S.; Li Y.; Liu W.; Zhao H.; Zhou Y.; Jiang Y.; Liu H.; Xia W.; Cai Z.; Xu S., Shen X., Associations between repeated measures of maternal urinary phthalate metabolites during pregnancy and cord blood glucocorticoids. Environ. Int., 2018, 121, 471-479.

4.        Huang, C.*; Chen, Z.; Gjelstad, A.; Pedersen-Bjergaard, S.; Shen, X.* Electromembrane extraction; TrAC, Trends Anal. Chem., 2017, 95, 47-56

5.        Shen, X.*; Huang, C.; Shinde, S.; Jagadeesan, K. K.; Ekström, S.; Fritz, E.; Sellergren, B.* Catalytic Formation of Disulfide Bonds in Peptides by Molecularly Imprinted Microgels at Oil/Water Interfaces; ACS Appl. Mater. Interfaces, 2016, 8, 30484-30491.

6.        Huang, C.; Seip, K. F.; Gjelstad, A.; Shen, X.*; Pedersen-Bjergaard, S. Combination of Electromembrane Extraction and Liquid-Phase Microextraction in a Single Step: Simultaneous Group Separation of Acidic and Basic Drugs; Anal. Chem., 2015, 87, 6951-6957

7.        Tu, Z.; Tang, H.; Shen, X.*, Particle-assisted semidirect breath figure method: A facile way to endow the honeycomb-structured Petri dish with molecular recognition capability; ACS Appl. Mater. Interfaces, 2014, 6, 12931-12938.

8.       Huang, C.; Shen, X.*, Janus molecularly imprinted polymer particles; Chem. Commun., 2014, 50, 2646-2649.

9.        Huang, C.; Shen, X.*, Breath figure patterns made easy; ACS Appl. Mater. Interfaces, 2014, 6, 5971-5976

10.    Shen, X.; Bonde, J. S.; Kamra, T.; Bülow, L.; Leo, J. C.; Linke, D.; Ye, L. Bacterial Imprinting at Pickering Emulsion Interfaces; Angew. Chem., Int. Ed., 2014, 53, 10687-10690.