Liegang Liu
Professor of Nutrition & Food Hygiene 
Department of Nutrition & Food Hygiene
* lgliu@mails.tjmu.edu.cn
Academic Areas
Nutrition Epidemiology/Chronic Disease Epidemiology/ Gene-Environment Interaction
Research Interests
> Nutritional epidemiology and prevention of obesity, type 2 diabetes, and cognitive impairment.
> Gene-environment interactions, biomarkers, and type 2 diabetes.
Selected Professional Affiliations
2013 Chair, Hubei Nutrition Society
2013 Executive board member, Chinese Nutrition Society
Courses Taught
Nutrition and Food Hygiene
Awards and Honors
2017 The Second Prize of Natural Science, Ministry of Education.
2014 The Second Prize of Natural Science, Hubei Provincial Department of Science & Technology
Education
1996‑1999 Ph.D., Department of Environmental Toxicology, Tongji Medical University
1989‑1992 Master's Degree of Medicine, Department of Nutrition and Food Hygiene, Tongji Medical University
1984‑1989 B.S., The Faculty of Preventive Medicine, Tongji Medical University
Professional/working Experience
2010-present Vice Dean, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
2004-present Professor and Chair, Department of Nutrition and Food Hygiene, Tongji Medical College, Huazhong University of Science and Technology
2001-2004 Associate Professor, Department of Nutrition and Food Hygiene, Tongji Medical College, Huazhong University of Science and Technology
2000‑2001 Visiting Scholar, Department of General, Visceral and Transplantation Surgery, Humboldt University
1995-2001 Lecturer, Department of Nutrition and Food Hygiene, Tongji Medical University
1992-1995 Research Assistant, Department of Nutrition and Food Hygiene, Tongji Medical University
Past and ongoing projects, funding, programs
> The mechanism of HO-1 over expression on preventing ethanol-induced liver damage in primary human hepatocytes. (supported by the grant from National nature science foundation, 2003.01- 2005.12)
> The intermediary mechanism of Hox gene on embryo congenital malformation caused by vitamin A deficiency in mouse embryo (supported by the grant from National nature science foundation, 2005.01- 2007.12)
> Flavanoid protects rat hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 (Supported by Program for New Century Excellent Talents in University, NCET-04-0707, 2005.01-2007.12)
> Effects of an extract of Proanthocyanidins on learning and memory in mice (supported by the grant from National nature science foundation, 2006.01- 2009.12)
> The Researching in the Effects of Dietary Interventionsin Women during the Puerperium. National Science and Technology Support Program, 2008.12-2010.12
> Safety Evaluation of Yunnan Pu-erh Teas. National Key Technology R&D Program of China. 2007BAD58B05, 2007.01-2010.12 (Co-investigator)
> Preventive and therapeutic effect of the natural anti-oxidant curcumin on Type 2 diabetes and the mechanism mediated via Nrf2/HO-1. (supported by the grant from National nature science foundation, 30872116, 2009.01-2011.12)
> Research of Generation and Control of Hazardous Substances in Animal Products-Toxicological Research of Hazardous Substances in Animal Products. Major Project of Chinese National Program s for Fundamental Research and Development (Co-investigator) 973 Program, 2009CB118803, 2009.01-2013.12
> The effects of HO/CO mediated neural signal transduction in procyanidins extracted from the lotus seedpod ameliorating age-related memory/cognition impairment (supported by the grant from National nature science foundation, 81072291, 2011.01-2013.12)
> Whole-genome association studies of Type 2 diabetes mellitus. The National High Technology Research and Development program of China. (Co-investigator) 863 Program, 2009AA022704, 2009-2013
> The Researching in Early Intervention and Prevention Measures of Obesity and Type 2 Diabetes Mellitus with Chinese Citizen. (Co-investigator) National Science and Technology Support Program, 2012-2016
> The neuroprotective effect of LSPC-regulated ERS-UPR signaling pathway on AD and its underlying mechanisms. (supported by the grant from National nature science foundation, 81472978, 2015.01-2018.12).
> Food contamination exposure group analysis and total diet study. (Co-investigator) The National Key Research and Development Program of China, 2017YFC1600500, 2017.01-2021.12
> Association of Advanced Glycation End-products and Type 2 Diabetes: Population-based Study and Mechanism Research (supported by the grant from National nature science foundation, 81773423, 2018.01-2021.12).
> Roles of Selenium and Supplementation in The Development of Type 2 Diabetes Mellitus (supported by the Major International (Regional) Joint Research Project, 81820108027, 2019.01-2023.12).
Select Publications
Books, patents
2018 Nutriology of Women and Children, People's Medical Publishing House (PMPH), ISBN 978-7-117-25304-8/R·25305
2017 Nutrition and Food Hygiene, People's Medical Publishing House (PMPH), ISBN 978-7-117-24427-5/R·24428
2016 Food Hygiology, Science Press ISBN 9787030464323
2016 Experimental Course of Preventive Medicine, Hubei Science & Technology Press, ISBN 9787535290267
2015 Food Contamination and Health, Hubei Science & Technology Press, ISBN 9787535283153
Journal Article
* Corresponding author
1. Sun T, Rong Y, Hu X, Zhu Y, Huang H, Chen L, Li P, Li S, Yang W, Cheng J, Yang X, Yao P, Hu FB*, Liu L*. Plasma Alkylresorcinol Metabolite, a Biomarker of Whole- Grain Wheat and Rye Intake, and Risk of Type 2 Diabetes and Impaired Glucose Regulation in a Chinese Population. Diabetes Care. 2018;41(3):440-445.
2. Li P, Zhong C, Li S, Sun T, Huang H, Chen X, Zhu Y, Hu X, Hu FB*, Liu L*. Plasma trimethylamine N-oxide, a microbiota-dependent metabolite, and risk of gestational diabetes mellitus. Am J Clin Nutr. 2018;108:603-610.
3. Shan Z, Sun T, Huang H, Chen S, Chen L, Luo C, Yang W, Yang X, Yao P, Cheng J, Hu FB*, Liu L*. Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes. Am J Clin Nutr. 2017;106(3):888-894.
4. Shan Z, Chen S, Sun T, Luo C, Guo Y, Yu X, Yang W, Hu FB*, Liu L*. U-Shaped Association between Plasma Manganese Levels and Type 2 Diabetes. Environ Health Perspect. 2016;124(12):1876-1881.
5. Shan Z, Ma H, Xie M, Yan P, Guo Y, Bao W, Rong Y, Jackson CL, Hu FB*, Liu L*. Sleep Duration and Risk of Type 2 Diabetes: A Meta-analysis of Prospective Studies. Diabetes Care. 2015;38(3):529-537.
6. Shan Z, Bao W, Zhang Y, Rong Y, Wang X, Jin Y, Song Y, Yao P, Sun C, Hu FB*, Liu L*. Interactions between Zinc Transporter-8 Gene (SLC30A8) and Plasma Zinc Concentrations for Impaired Glucose Regulation and Type 2 Diabetes. Diabetes. 2014;63(5):1796-1803.
7. Luo C, Zhang Y, Ding Y, Shan Z, Chen S, Yu M, Hu FB*, Liu L*. Nut consumption and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis. Am J Clin Nutr. 2014;100(1):256-269.
8. Gao H, Meng J, Xing H, Nie S, Xu M, Zhang S, Jin Y, Sun T, Huang H, Zhang H, Wang D, Liu L*. Association of heme oxygenase-1 with the risk of polycystic ovary syndrome in non-obese women. Hum Reprod. 2014;29(5):1058-1066.
9. Rong Y, Chen L, Zhu T, Song Y, Yu M, Shan Z, Sands A, Hu FB*, Liu L*. Egg consumption and risk of coronary heart disease and stroke: dose-response meta-analysis of prospective cohort studies. BMJ. 2013;346:e8539.
10. Wang X, Bao W, Liu J, Ouyang Y, Wang D, Rong S, Xiao X, Shan Z, Zhang Y, Yao P, Liu L*. Inflammatory Markers and Risk of Type 2Diabetes：A systematic review and meta-analysis. Diabetes Care. 2013;36:166-175.
