Ping Yao
Professor of Nutrition & Food Hygiene
Department of Nutrition & Food Hygiene
* yaoping@mails.tjmu.edu.cn
Academic Areas
Nutrition and Chronic Disease/Molecular Nutrition
Research Interests
> Pathogenesis and nutritional intervention of alcoholic liver diseases
> Iron overload and chronic diseases: nutritional intervention by phytochemicals
> Iron metabolism disorders and NAFLD: Pathogenesis and nutritional intervention by quercetin
> Nutritional epidemiology on NAFLD
Selected Professional Affiliations
2016 Chair, Special Committee on Food Hygiene, Wuhan Preventive Medical Association
2013 Executive board member and Vice Secretary-General, Hubei Nutrition Society
Courses Taught
Nutrition and Food Hygiene/Preventive Medicine/Clinical Nutrition/Health Food/Introduction of Medicine (Preventive medicine)
Awards and Honors
2018 Analysis of HO-1 susceptibility loci, dietary nutrition risk factors and related mechanisms in type 2 diabetes mellitus. Second Prize in Natural Science, Ministry of Education (2nd)
2014 Mechanism of HO-1 induced by plant flavonoids against alcoholic liver diseases. Second Prize in Natural Science of Hubei Province (2nd)
2014 The innovation and practice of human cultivation mode in preventive medicine oriented by ability cultivation. Second Prize of National Teaching Achievement (5th)
2011 Basic research on mechanism and intervention of alcohol toxicity. Third Prize of China Medical Science and Technology Award (5th)
Education
2002-2005 Ph.D., Nutrition and Food Hygiene, Huazhong University of Science & Technology, Wuhan, China.
1995-1998 M.D., Food Chemistry & Analysis, Huazhong Agricultural University, Wuhan, China.
1990-1994 B.S., Agronomy, Hubei Agricultural College (Yangtze University), Jinzhou, China.
Professional/working Experience
2013-present Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
2006-2013 Associate Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
2001-2006 Lecturer, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
1998-2001 Teaching assistant, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Past and ongoing projects, funding, programs
> 2017-2020: Joint disequilibrium of NCOA4-meidated ferritinophagy and LIP in the pathogenesis of alcoholic hepatic iron overload and quercetin intervention (NFSC 81673164).
> 2015-2018: Iron deposition in atherosclerosis plaque and quercetin intervention: signaling regulation of hepcidin autocrine from macrophages (NFSC 81472979)
> 2012-2015: Mechanisms of Disorder in iron overload and labile iron pool induced by alcohol and intervened by quercetin (81172658)
> 2009-2012: Crucial molecular and signaling pathways involved in HO-1 induction by quercetin against alcoholic liver diseases (NCET-08-0222)
> 2009-2011: Molecular mechanisms of quercetin/HO-1 indcution/metabolites on alcoholic liver diseases (NFSC 30872117)
> 2006-2008: Nrf2/HO-1-medicated protection of quercetin against alcoholic liver damage (NFSC 30500405)
>
Select Publications
Books, patents
1. Preventive medicine experimental course: Associate Editor, Hubei Science & Technology Press, 2016
2. Food contamination and health: Associate Editor, Hubei Science & Technology Press, 2015
Journal Article
* Corresponding author (selected)
1. Liu P, Lin H, Xu Y, Zhou F, Wang J, Liu J, Zhu X, Guo X, Tang Y*, Yao P*. Frataxin-Mediated PINK1-Parkin-Dependent Mitophagy in Hepatic Steatosis: The Protective Effects of Quercetin. Mol Nutr Food Res. 2018 Jun 23:e1800164.
2. Xiao L, Luo G, Tang Y*, Yao P*. Quercetin and iron metabolism: What we know and what we need to know. Food Chem Toxicol. 2018 Apr;114:190-203.
3. Guo X, Chen M, Zeng H, Liu P, Zhu X, Zhou F, Liu J, Zhang J, Dong Z, Tang Y*, Gao C, Yao P*. Quercetin Attenuates Ethanol-Induced Iron Uptake and Myocardial Injury by Regulating the Angiotensin II-L-Type Calcium Channel. Mol Nutr Food Res. 2018 Mar;62(5): 1700772.
4. Tang Y, Li J, Gao C, Xu Y, Li Y, Yu X, Wang J, Liu L, Yao P*. Hepatoprotective Effect of Quercetin on Endoplasmic Reticulum Stress and Inflammation after Intense Exercise in Mice through Phosphoinositide 3-Kinase and Nuclear Factor-Kappa B. Oxid Med Cell Longev. 2016;2016:8696587.
5. Li Y, Chen M, Xu Y, Yu X, Xiong T, Du M, Sun J, Liu L, Tang Y*, Yao P*. Iron-Mediated Lysosomal Membrane Permeabilization in Ethanol-Induced Hepatic Oxidative Damage and Apoptosis: Protective Effects of Quercetin. Oxid Med Cell Longev. 2016;2016:4147610.
6. Tang Y, Li Y, Yu H, Gao C, Liu L, Chen S, Xing M, Liu L, Yao P*. Quercetin prevent ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway. J Nutr Biochem. 2014. 25(6): 675-682
7. Liu L, Tang Y, Gao C, Li Y, Chen S, Xiong T, Li J, Du M, Gong Z, Chen H, Liu L, Yao P*. Characterization and biodistribution in vivo of quercetin-loaded cationic nanostructured lipid carriers. Colloids Surf B Biointerfaces. 2014, 115 (1 March 2014), 125–131
8. Li Y, Gao C, Shi Y, Tang Y, Liu L, Xiong T, Du M, Xing M, Liu L, Yao P*. Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway. Toxicol Appl Pharmacol. 2013 November 15, 273 (1) : 53–58.
9. Tang Y, Gao C, Shi Y, Zhu L, Hu X, Wang D, Lv Y, Yang X, Liu L, Yao P*. Quercetin attenuates ethanol-derived microsomal oxidative stress: Implication of haem oxygenase-1 induction. Food Chem 2012 June 15, 132(4): 1769-1774
10. Yao P, Nussler A, Liu L, Hao L, Song F, Schirmeier A, Nussler N*. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1via the MAPK/Nrf2 pathways. J Hepatol 2007 Aug; 47(2): 253-61
