Jixuan Ma

【Source: | Date:2019-09-05 】

Associate Professor of Occupational and Environmental Health

Department of Occupational and Environmental Health


Academic Areas 

Environmental Epidemiology/ Industrial Toxicology

Research Interests

1.      Epidemiological studies to investigate the contribution of environmental pollution and genetic susceptibility to the development of cardiopulmonary disease.

2.      Toxicological studies to explore mechanism of silica-induced pulmonary fibrosis.


2014.09-2017.06.  Ph.D., Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

2011.09-2014.06.  Joint Master, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.

2007.09-2011.06.  B, S., School of Public Health, Xinjiang Medical University, Xinjiang, China

Professional/working Experience

2022.04- present.  Associate Professor, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.

2019.11-2022.04.   Lecturer, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.

2017.11-2019.11.     Research Fellow, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.

Select Publications

Journal Article

1.Ma J, Tan Q, Nie X, Zhou M, Wang B, Wang X, Cheng M, Ye Z, Xie Y, Wang D, Chen W*. Longitudinal relationships between polycyclic aromatic hydrocarbons exposure and heart rate variability: Exploring the role of transforming growth factor-β in a general Chinese population. J Hazard Mater. 2022 Mar 5;425:127770.

2.Wang X, Bin Wang, Zhou M, Xiao L, Xu T, Yang S, Nie X, Xie L, Yu L, Mu G, Ma J*, Chen W*. Systemic inflammation mediates the association of heavy metal exposures with liver injury: A study in general Chinese urban adults. J Hazard Mater. 2021 Oct 5;419:126497. (* co-corresponding author)

3.Ma J1, Hao X1, Nie X, Yang S, Zhou M, Wang D, Wang B, Cheng M, Ye Z, Xie Y, Wang C*, Chen W*. Longitudinal relationships of polycyclic aromatic hydrocarbons exposure and genetic susceptibility with blood lipid profiles. Environ Int. 2022 Apr 25;164:107259.

4.Ma J, Zhou Y, Wang D, Guo Y, Wang B, Xu Y, Chen W*. Associations between essential metals exposure and metabolic syndrome (MetS): Exploring the mediating role of systemic inflammation in a general Chinese population. Environ Int. 2020 Jul;140:105802.

5.Ma J, Xie Y, Xu Y, Gu P, Zhang Y, Fan L, Zhou Y, Wang H, Zhou T, He J, Wang D, Chen W*. Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo. Journal of Environmental Sciences. (2022, Available online, In press)

6.Ma J, Xie Y, Zhou Y, Wang D, Cao L, Zhou M, Wang X, Wang B, Chen W*. Urinary copper, systemic inflammation, and blood lipid profiles: Wuhan-Zhuhai cohort study. Environ Pollut. 2020 Dec;267:115647.

7.Xie Y1, Ma J1, Xie L, Li W, Yang M, Gu P, Zhang Y, Fan L, Wang D, Chen W*. Inhibition of Gas6 promotes crystalline silica-induced inflammatory response of macrophages via blocking autophagy flux. Environ Toxicol. 2022 Apr 19. (1 co-first author)

8.Ma J, Zhou Y, Li W, Xiao L, Yang M, Tan Q, Xu Y, Chen W. Association between Plasma HMGB-1 and Silicosis: A Case-Control Study. Int J Mol Sci. 2018 Dec 14;19(12):4043.

9.Ma J, Zhou Y, Liu Y, Xiao L, Cen X, Li W, Guo Y, Kim M, Yuan J, Chen W. Association between urinary polycyclic aromatic hydrocarbon metabolites and dyslipidemias in the Chinese general population: A cross-sectional study. Environ Pollut. 2019 Feb;245:89-97.

10.Ma J1, Wu L1, Zhou Y, Zhang H, Xiong C, Peng Z, Bao W, Meng T, Liu Y. Association between BMI and semen quality: an observational study of 3966 sperm donors. Hum Reprod. 2019 Jan 1;34(1):155-162. (1 co-first author)

11.Ma J, Xu Y, Li W, Zhou Y, Wang D, Yang M, Wang B, Chen W. High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis. Toxicol Lett. 2020 May 17;330:134-143.

12.Ma J, Cui X, Rong Y, Zhou Y, Guo Y, Zhou M, Xiao L, Chen W. Plasma LncRNA-ATB, a Potential Biomarker for Diagnosis of Patients with Coal Workers' Pneumoconiosis: A Case-Control Study. Int J Mol Sci. 2016 Aug 22;17(8):1367.

13.He P, Yang C, He D, Zhao S, Xie Y, Wang H, Ma J*. Blood Lead, Systemic Inflammation, and Blood Pressure: Exploring Associations and Mediation Effects in Workers Exposed to Lead. Biol Trace Elem Res. 2021 Jul;199(7):2573-2581.

14.Cao L, Zhou Y, Tan A, Shi T, Zhu C, Xiao L, Zhang Z, Yang S, Mu G, Wang X, Wang D, Ma J*, Chen W*. Oxidative damage mediates the association between polycyclic aromatic hydrocarbon exposure and lung function. Environ Health. 2020 Jul 2;19(1):75. (* co-corresponding author)

15.Hou J1, Sun H1, Ma J1, Zhou Y, Xiao L, Xu T, Cheng J, Chen W, Yuan J. Impacts of low socioeconomic status and polycyclic aromatic hydrocarbons exposure on lung function among a community-based Chinese population. Sci Total Environ. 2017 Jan 1;574:1095-1103. (1 co-first author)