Weihong Chen

【Source: | Date:2019-08-05 】


Professor of Occupational and Environmental Health

Adjunct Professor in Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong

Department of Occupational and Environmental Health

* wchen@mails.tjmu.edu.cn

Academic Areas

Occupational and Environmental Health / Occupational Epidemiology

Research Interests

Health effects of particulate matter exposure, especially industrial dust and fiber.

The pathogenic mechanism of particle matter to cause cardiopulmonary diseases.

Evaluation of personal respiratory protection equipment.

Selected Professional Affiliations

1.         Deputy Director of the Occupational Health Branch in Hubei Preventive Medicine Association

2.        Member of China Occupational Health Standards Committee

3.        Standing Member of the Occupational Health Professional Committee of China Occupational Safety and Health Association

4.        Editorial Board, Chinese Journal of Occupational Health and Occupational Diseases

5.        Editorial Board, Environmental and Occupational Medicine

6.        Editorial Board, Journal of Industrial Hygiene and Occupational Diseases

7.        Editorial Board, Current Medicine Science

Courses Taught

Occupational health and occupational medicine / Preventive medicine

Awards and Honors

2006     Alice Hamilton Award, US NIOSH

2007     First class prizes of Hubei Scientific and Technology Progress Award

2007     Second class prize of Ministry of Education Award for Scientific and Technological Progress

2014     Second class prizes of Chinese State Scientific and Technological Progress Award


1999-2001        MD, University of Duisburg-Essen EssenGermany

1990-1993        MS, Tongji Medical University, Wuhan, China

1985-1990        BM, Tongji Medical Uiversity, Wuhan, China

Professional/working Experience


Professor and chief School of Public Health, School of Public Health, Huazhong University of Science and Technology.


Associated Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology.


Research Assistant, then senior researcher (from Sep,2002), Institute of Hygiene and Occupational Medicine, Medical School, University of Essen, Germany.


Visiting scientist, National Institute for Occupational Safety and Health (NIOSH), Centers for Diseases Control and Prevention (CDC), USA.


Lecturer, School of Public Health, Tongji Medical University, China

Past and ongoing projects, funding, programs

2016-2019         Molecular epidemiological study of decline in lung function and chronic obstructive pulmonary disease caused by airborne fine particulate matter. key project in National Natural Science Foundation of China (NSFC 91543207). (PI)

2016-2019         The relationship between air pollutant and altered lung function or chronic obstructive pulmonary disease. Key research and development program of Ministry of science and technology (2016YFC1303903). (PI)

2019-2022         Mechanism of Thyroid hormone mediated immune response in inflammatory reaction and pulmonary fibrosis induced by crystalline silica. National Natural Science Foundation of China, (NSFC 81872593). (PI)

2011-2015          The study on early respiratory injury of PM and its mechanisms. (sub project of Basic studies on health hazards caused by ambient particulate matter). National Key Basic Research and Development Program (2011CB503804). (PI).

2013-2015         Research on human exposure assessment technology for typical environmental PCDD/Fs exposure. Environmental protection public welfare industry research special.  (PI)

2014-2017.        The role and mechanism of TAM/Gas6 in the inflammation response and fibrosis induced by crystalline silica. National Natural Science Foundation of China (NSFC 81372967) in China. (PI)

2016-2019         The role and mechanism of Nalp3 inflammasome in work-related knee osteoarthritis. National Natural Science Foundation of China (NSFC 81573121). (PI)

2012-2019         Determination of Occupational Hazards and Possible Health Damage in one thermal ceramic factory. (PI)

2010-2012         The role and Mechanism of Nalp3 Inflammasome in Quartz Dust Fibrosis Natural Science Foundation of China (NSFC30972451).

2009-2012        Analysis and Assessment of Medical Monitoring Performance and Cost Effectiveness of Dust Workers. Hong Kong Pneumoconiosis Compensation Foundation. (Co-PI)

2006-2012        Study on head anthropometric and study factors affecting the containment of filter-type respirators. National Institute for Occupational Safety and Health (PI).

2006-2008       The role of neurogenic inflammatory response in the early stages of quartz damage. Natural Science Foundation of China (NSFC 30571553).(PI)

2004-2012        Risk assessment of silicosis and lung cancer in workers exposed to quartz mixed dust. German Trade Union Institute for Occupational Safety and Health (BIA1074).(PI)


Select Publications

Books, patents

1.        Chen W, Respiratory Diseases Among Dust Exposed Workers. In Respiratory Diseases (Mostafa Ghanei), ISBN 978-953-307-964-6. Croatia, InTech, 2012, DOI 10.5772/32357

Journal Article

*Corresponding author

1.         Zhou Y, Mu G, Liu Y, Xiao L, Ma J, Wang B, Shi T, Tan A, Yuan J, Chen W*. Urinary polycyclic aromatic hydrocarbon metabolites, Club cell secretory protein and lung function. Environ Int. 2018 Feb; 111:109-116.

2.        Liu Y, Zhou Y, Hnizdo E, Shi T, Steenland K, He X, Chen W*. Total and cause-specific mortality risk associated with low-level exposure to crystalline silica: a 44-year cohort study from China. Am J Epidemiol, 2017,186(4):481-490.

3.        Zhou Y, Sun H, Xie J, Song Y, Liu Y, Huang X, Zhou T, Rong Y, Wu T, Yuan J*, Chen W*. Urinary Polycyclic Aromatic Hydrocarbon Metabolites and Altered Lung Function in Wuhan, China. Am J Resp Crit Care. 2016,193(8): 835-846

4.        Guo J, Shi T, Cu X, Rong Y, Zhou T, Zhang Z, Liu Y, Shen Y, Chen W*. Effects of silica exposure on the cardiac and renal inflammatory and fibrotic response and the antagonistic role of interleukin-1 beta in C57BL/6 mice. Arch Toxicol. 2016, 90 (2): 247-258

5.        Liu Y, Rong Y, Steenland K, Christiani DC, Huang X, Wu T, Chen W*. Long-term Exposure to Crystalline Silica and Risk of Heart Disease Mortality. Epidemiology. 2014 , 25(5):689-96.

6.        Liu Y, Steenland K, Rong Y, Hnizdo E, Huang X, Zhang H, Shi T, Sun Y, Wu T, Chen W*. Exposure-Response Analysis and Risk Assessment for Lung Cancer in Relation to Silica Exposure: A 44-year Cohort Study of 34,018 Workers. Am J Epidemiol. 2013, 178(9):1424-33.

7.        Guo J, Gu N, Chen J, Shi T, Zhou Y, Rong Y, Zhou T, Yang W, Cui X, Chen W*. Neutralization of interleukin1 beta attenuates silicainduced lung inflammation and fibrosis in C57BL/6 mice. Arch Toxicol. 2013, 87:1963–1973.

8.       Chen W*, Liu Y, Wang H, Hnizdo E, Sun Y, Su L, Zhang X, Weng S, Bochmann F, Hearl F, Chen J, Wu T*. Long-Term Exposure to Silica Dust and Risk of Total and Cause-Specific Mortality in Chinese Workers: A Cohort Study. PLoS Med 2012,9(4),e1001206

9.        Leung CC*, Yu ITS, Chen W. Silicosis. Lancet. 2012,379:2008-18

10.    Chen W*, Zhuang Z, Attfield MD, Chen BT, Gao P, Harrison JC, Fu C, Chen J, and Wallace WE. Exposure to silica and silicosis among tin miners in China: exposure-response analyses and risk assessment.  Occup Environ Med 2001,58:31-37.